Research attention has been drawn to honey’s nutritional status and beneficial properties for human health. This study aimed to provide a bibliometric analysis of honey’s antioxidant and antimicrobial properties. The research advancements within this field from 2001 to 2022 were addressed using the Scopus database, R, and VOSviewer. Of the 383 results, articles (273) and reviews (81) were the most common document types, while the annual growth rate of published manuscripts reached 17.5%. The most relevant topics about honey’s antimicrobial and antioxidant properties were related to the agricultural and biological sciences, biochemistry, and pharmacology. According to a keyword analysis, the most frequent terms in titles, abstracts, and keywords were honey, antimicrobial, antioxidant, bee, propolis, phenolic compounds, wound, antibacterial, anti-inflammatory, and polyphenols. A trend topic analysis showed that the research agenda mainly encompassed antioxidants, pathogens, and anti-infection and chemical agents. In a co-occurrence analysis, antioxidants, anti-infection agents, and chemistry were connected to honey research. The initial research focus of this domain was primarily on honey’s anti-inflammatory and antineoplastic activity, wound healing, and antibacterial agents. The research agenda was enriched in the subsequent years by pathogens, propolis, oxidative stress, and flavonoids. It was possible to pinpoint past trends and ongoing developments and provide a valuable insight into the field of honey research.
To study the antibacterial effect of different Greek honeys, samples of citrus honey, Saturja spp. Honey, and oregano and sage honey were collected directly from producers. Manuka honey and artificial honey were used as controls. The honeys were diluted in various concentrations to determine the minimum inhibitory concentration (MIC) and were also placed in agar wells to determine the inhibitory zones of growth. The bacteria tested were two reference strains and five pathogens isolated from patients with various dental ailments. A series of samples were diluted with artificial saliva instead of distilled water to simulate the conditions in the oral cavity. The results show that in most cases the Greek honeys, and particularly the citrus honey and the oregano and sage honey, outperformed the antibacterial activity of manuka honey against all tested bacteria. This performance was due to the hydrogen peroxide as well as to other components of the honeys, that is, peptides and other substances such as phenolic compounds and flavonoids. Artificial saliva enhanced the antibacterial effect of the honeys in comparison to distilled water.
Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract affecting millions of patients worldwide. The gut microbiome partly determines the pathogenesis of both diseases. Even though probiotics have been widely used as a potential treatment, their efficacy in inducing and maintaining remission is still controversial. Our study aims to review the present-day literature about the possible role of probiotics in treating inflammatory bowel diseases in adults. This research was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. We included studies concerning adult patients who compared probiotics with placebo or non-probiotic intervention. We identified thirty-three studies, including 2713 patients from fourteen countries. The role of probiotics in Crohn’s disease was examined in eleven studies. Only four studies presented statistically significant results in the remission of disease, primarily when used for three to six months. On the other hand, in twenty-one out of twenty-five studies, probiotics proved effective in achieving or maintaining remission in ulcerative colitis. Supplementation with Bifidobacterium sp. or a combination of probiotics is the most effective intervention, especially when compared with a placebo. There is strong evidence supporting the usage of probiotic supplementation in patients with ulcerative colitis, yet more research is needed to justify their efficacy in Crohn’s disease.
Internet and Communication Technology (ICT) tools have been already introduced in every aspect of environmental science. Regarding climate change, research trends and developments on ICT help realize how ICT evolved and its potential future role in climate change. This study aimed to assess ICT solutions in climate change research trends using the Scopus database, bibliometric indicators, and network visualization. After a preliminary application of various combinations, the phrase “ICT and climate change” was used with language selection “English” from 01/01/1999 to 01/12/2021. A collection of 453 articles published in scientific journals and conference proceedings was revealed, which allowed the visualization mapping of the research agenda in the field of ICT and climate change. The most relevant topics are related to Computer Science, Engineering, Environmental and Social sciences. It has been found that a significant amount of documents were published after 2008. The Royal Institute of Technology-KTH was the most productive institution, followed by the Consiglio Nazionale Delle Ricerche and the Universitetet I Oslo. In addition, the dominant countries in the respective research area were the United Kingdom, Italy, United States, India and Sweden. According to citations, most of the published research activity emerged in various journals, like Environment and Planning, Cities and Energies. It was possible to spot past trends and ongoing development, intending to introduce ICT tools in climate change impacts and examine the issues expected to be pertinent in the future.
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