Annular lichenoid dermatitis of youth is a lichenoid dermatosis of unknown etiology. It mostly affects children and adolescents and has well-defined clinical and histological characteristics that permit a diagnosis. We present 2 new cases of annular lichenoid dermatitis of youth with classical clinical features in 2 girls, aged 2 and 4 years. The histologic findings, however, differed from those reported in the literature in that the lichenoid inflammatory infiltrate was located primarily at the top of the dermal papillae and not at the tips of the rete ridges. In both cases, the lesions regressed spontaneously without treatment.
Additional Supporting Information may be found in the online version of this article at the publisher's website: Fig S1. Molecular findings. (a, b) Partial sequence of PKP1 exon 3 in the patient and control. (c) Quantitative real-time polymerase chain reaction. (d) Immunofluorescence staining of control and affected skin.Funding sources: none. Conflicts of interest: none declared.
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