Ablative fractional lasers were introduced for treating facial rhytides. Few studies have compared fractional CO and Er:YAG lasers on cutaneous photodamages by a split trial. The aim of the present study was to compare these modalities in a randomized controlled double-blind split-face design with multiple sessions and larger sample size compared to previous studies done before. Forty patients with facial wrinkles were enrolled. Patients were randomly assigned to receive three monthly treatments on each side of the face, one with a fractional CO and one with a fractional Er:YAG laser. The evaluations included investigating clinical outcome determined by two independent dermatologists not enrolled in the treatment along with measuring skin biomechanical property of cheeks using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT). Moreover, possible side effects and patients' satisfaction have been recorded at baseline, 1 month after each treatment, and 3 months after the last treatment session. Clinical assessment showed both modalities significantly reduce facial wrinkles (p value < 0.05), with no appreciable difference between two lasers. Mean CRRT values also decreased significantly after the laser treatment compared to the baseline in both laser groups. There was no serious long-standing adverse effect after both laser treatments, but the discomfort was more pronounced by the participants after CO laser treatment. According to the present study, both fractional CO and fractional Er:YAG lasers show considerable clinical improvement of facial skin wrinkles with no serious adverse effects, but post-treatment discomfort seems to be lower with Er:YAG laser.
Introduction: Wound myiasis is the infestation of human wounds by dipterous larvae due to Calliphora, Cochliomyia, Phormia and Lucilia species. Ophthalmomyiasis is rare and is classified into external, internal, or orbital categories. External ophthalmomyiasis (the most common type) refers to an infestation of the conjunctiva and palpebra, mainly caused by the sheep bot fly (Oestrus ovis). Case Presentation: We describe a young male with wound and ocular myiasis due to Lucilia sericata, who had a history of trauma to his scalp following a car accident during the previous few days and was left about three days in an inaccessible area. He complained of painful parietal ulcer and sudden onset of left eye redness with pain. Physical examination revealed wound and conjunctival myiasis. The larvae were manually extracted by forceps and seven days later, the lesions showed improvement. Conclusions: Early diagnosis is required for the management of human myiasis. If we don't properly recognize and treat ophthalmomyiasis, it can progress rapidly and can result in destruction of orbital tissues. The main treatment modality includes removal of the larvae and if necessary, surgical debridement.
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