Fourteen female subjects were tested during the menstrual (days 14), foilicular (days 6-12), luteal (days 17-21), and premenstrual (days 23-27) phases of their menstrual cycles. Of the tests used (arm-hand steadiness, galvanic skin response to an auditory stimulus, reaction timesimple and choice, time estimation, and digit-symbol substitution), only arm-hand steadiness showed statistically significant fluctuations over the course of the cycle. Daily self-ratings of various symptoms and moods showed no significant changes when the appropriate statistical techniques were used; parametric techniques suggested fluctuations in reports of pain, bloatedness, hunger, hours of sleep, and pressure of immediate academic work.
With the use of a pre-and posttest design, the effect of a one-week camping experience researched knowledge, attitude toward diabetes, and self-concept of diabetic and nondiabetic children in an integrated residential camp. Subjects for this study were 63 children with diabetes and 18 children without, ages 8 to 14. A modified Etzwiler Diabetic Knowledge Questionnaire, a modified Attitude toward Disabled People Scale, and a Piers-Harris Children's Self-concept Scale were administered on days one and six. Subject characteristics considered to be related to the variables under study were assessed. Paired t-tests, analysis of covariance with repeated measures, and Pearson correlation techniques were used in data analysis. While both the diabetic and nondiabetic groups significantly increased in knowledge about the disease, in neither group was their change in attitude toward the disease significant nor did the nondiabetic subjects demonstrate a statistically significant difference on this variable. Age of onset was inversely correlated with knowledge gain scores, and self-concept were positively correlated with the knowledge scores. The groups did not differ in
A man in his 20s presented with a 2-week history of fever, fatigue and diarrhoea. On arrival to the emergency department, he had clinical findings of sepsis. The care team initially suspected sepsis secondary to bacterial colitis and administered antibiotics. Further workup including a stool PCR assay for gastrointestinal pathogens failed to establish a diagnosis, and he had no evidence of immune compromise. Colonoscopy revealed mucosal ulceration presumed to be ulcerative colitis. Histopathology obtained after discharge revealed severe colitis with cytomegalovirus (CMV) inclusions. Serological studies indicated a primary CMV infection. To our knowledge, this is the first report of a primary CMV infection presenting as severe colitis and systemic disease in a young immunocompetent patient without underlying disease.
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