HighlightsCCDC66 protein is expressed throughout the early postnatal development in the WT mouse brain.CCDC66 protein expression levels in the olfactory bulb are comparable to the retina in adult (3-month-old) WT mice.The Ccdc66-deficient retinal degeneration mouse model also exhibits impairment of the olfactory system.Severe degeneration was detected in olfactory bulb glomeruli of adult Ccdc66 -/- mice.Ccdc66-deficient mice show alteration of olfaction-related behavior at advanced age.
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