A rare case of a combination of vulgar psoriasis and squamous cell carcinoma of the penis in a patient with discoid lupus erythematosus is described. The literature data on the comorbidity of dermatoses are given.
INTRODUCTION: The study included 68 patients with idiopathic hand eczema.
RESULTS: Neurological symptoms were detected in 75% of patients; the most frequently recorded symptoms were myodefans (66.1%) and radicular sensory impairment (52.9%). Disorders of the psychoemotional state of patients were manifested by signs of depression in 38.1% of patients and personal and reactive anxiety in 63.8% and 72% of patients, respectively. The prevalence of indicators of depression and reactive anxiety and personal anxiety were found in men and women, respectively. The manifestation of the psychovegetative syndrome was found in 75% of patients. Degenerative-dystrophic changes in the spine were observed in 91.1% of patients, and two or more conditions were observed in 52.9% of the examined patients. The most pronounced changes were observed in C5C7 segments of the spine, and in 57.3% of the patients, these changes were associated with the side of the inflammatory process on the skin.
CONCLUSION: The obtained data substantiate the correction of the psychovegetative syndrome and treatment of dorsopathy in hand eczema.
Aim. To elucidate peculiarities of autorosette formation (ARF), immunological status and associated factors in patients with type 2 diabetes mellitus. Materials and methods. The study included 148 patients with DM2 and 63 practically healthy subjects. The following parameters were measured:the number of autorosettes in peripheral blood, C-reactive protein level, and humoral immunity (from blood immunoglobulin levels); spontaneousand induced TNB tests were performed. Results. Patients with DM2 suffered disturbances of carbohydrate metabolism and had an elevated number of autorosettes in peripheral blood, dysimmunoglobulinemia,increased level of acute phase protein, impaired functional activity of neutrophils. Conclusion. Intensity of ARF increases with duration of DM2 and a rise in AP. Patients with long-standing severe DM2, AH, micro- and macroalbuminurea,hyperglycemia, and triglyceridemia experience deterioration of immunological status.
В статье представлен аналитический обзор научной литературы на тему «верблюжьих» антител, их открытия, структурных отличий от классических иммуноглобулинов и их применения в генной инженерии, биологических исследованиях и в медицине, в частности, в онкологической терапии.
This paper presents the current data regarding the epidemiology, risk factors, diagnosis, clinical manifestations, and treatment of Erythroplasia of Queyrat (EQ). The possibility of using photodynamic therapy (PDT) for EQ is analyzed, and clinical observation of a patient with EQ who underwent PDT with an external gel photosensitizer based on E6 chloride is described.
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