Boronic acids are valued by organic chemists for their important role in the synthesis of biphenyls via a palladium(0) catalysed cross-coupling reaction with aryl halides (Suzuki reaction). Despite their synthetic utility and known biological activities heterocyclic boronic acids feature less frequently often due to difficulties in their synthesis. This paper provides an overview of the synthesis and applications of a range of heterocyclic boronic acids. 5Conclusions
Resveratrol glucuronides inhibit cell growth by G1 arrest and cyclin D1 depletion, and our results strongly suggest a role for A3 adenosine receptors in this inhibition.
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