Background and aims: The causes of relapses of ulcerative colitis (UC) are unknown. Dietary factors have been implicated in the pathogenesis of UC. The aim of this study was to determine which dietary factors are associated with an increased risk of relapse of UC. Methods: A prospective cohort study was performed with UC patients in remission, recruited from two district general hospitals, who were followed for one year to determine the effect of habitual diet on relapse. Relapse was defined using a validated disease activity index. Nutrient intake was assessed using a food frequency questionnaire and categorised into tertiles. Adjusted odds ratios for relapse were determined using multivariate logistic regression, controlling for non-dietary factors. Results: A total of 191 patients were recruited and 96% completed the study. Fifty two per cent of patients relapsed. Consumption of meat (odds ratio (OR) 3.2 (95% confidence intervals (CI) 1.3-7.8)), particularly red and processed meat (OR 5.19 (95% CI 2.1-12.9)), protein (OR 3.00 (95% CI 1.25-7.19)), and alcohol (OR 2.71 (95% CI 1.1-6.67)) in the top tertile of intake increased the likelihood of relapse compared with the bottom tertile of intake. High sulphur (OR 2.76 (95% CI 1.19-6.4)) or sulphate (OR 2.6 (95% CI 1.08-6.3)) intakes were also associated with relapse and may offer an explanation for the observed increased likelihood of relapse. Conclusions: Potentially modifiable dietary factors, such as a high meat or alcoholic beverage intake, have been identified that are associated with an increased likelihood of relapse for UC patients. Further studies are needed to determine if it is the sulphur compounds within these foods that mediates the likelihood of relapse and if reducing their intake would reduce relapse frequency.

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HAV interacts with the host signalling mechanism, and HAV VP3, different from HBX and hepatitis C core protein, may activate only SRE-associated intracellular signalling, a pathway associated with cell proliferation and differentiation.

Gone are the days of robots solely operating in isolation, without direct interaction with people. Rather, robots are increasingly being deployed in environments and roles that require complex social interaction with humans. The implementation of human-robot teams continues to increase as technology develops in tandem with the state of human-robot interaction (HRI) research. Trust, a major component of human interaction, is an important facet of HRI. However, the ideas of trust repair and trust violations are understudied in the HRI literature. Trust repair is the activity of rebuilding trust after one party breaks the trust of another. These trust breaks are referred to as trust violations . Just as with humans, trust violations with robots are inevitable; as a result, a clear understanding of the process of HRI trust repair must be developed in order to ensure that a human-robot team can continue to perform well after a trust violation. Previous research on human-automation trust and human-human trust can serve as starting places for exploring trust repair in HRI. Although existing models of human-automation and human-human trust are helpful, they do not account for some of the complexities of building and maintaining trust in unique relationships between humans and robots. The purpose of this article is to provide a foundation for exploring human-robot trust repair by drawing upon prior work in the human-robot, human-automation, and human-human trust literature, concluding with recommendations for advancing this body of work.

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