favorable outcome than those whose nodes are negative by both approaches. Thus, there is a strong likelihood that, in the future, molecular approaches will be used in parallel with standard histology. Conclusion: The sentinel node technique is the most accurate staging technique currently available for melanoma patients and provides predictive information on non-sentinel node tumor status, likelihood of recurrence and death from melanoma. It is also applicable to other tumors. The identification of a tumor-free sentinel node spares a majority of patients unnecessary nodal surgery. The effect of the approach on survival will be known when outcomes from current studies are evaluated. Source of funding: CA, 29605.
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