RESUMENCaso clínico: El Complejo de Carney (CNC) es un raro síndrome multineoplásico, autosómico dominante; caracterizado por presentar mixomas, lesiones pigmentadas en la piel, tumores endocrinos y manifestaciones oculares. Discusión: Analizamos los signos oftalmológicos de este síndrome, los cuales suelen preceder al componente más serio del mismo, el mixoma cardíaco.Palabras clave: Síndrome de Carney, trastornos pigmentarios, mixomas, tumores endocrinos.
COMUNICACIÓN CORTA
ABSTRACTCase report: Carney complex (CNC) is a multiple neoplasia syndrome, inherited in an autosomal dominant manner, characterized by myxomas, spotty skin pigmentation, endocrine tumors and ophthalmic abnormalities. Discussion: We report the ocular findings which usually precede the most serious component of the complex, the cardiac myxoma (Arch Soc Esp Oftalmol 2006; 81: 709-712).
Basic fibroblast growth factor (bFGF) has shown a neuroirophic effect in the neurons of several CNS areas. In vivo, it contributes to restore neurochcmical and morphological deficits in different rodent models of brain damage, including rats with brain damage induced by hypoxia/ischemia when FGF was intramuscularly (i.m.) administered. Toxicological and immunological studies performed in rats, mice and volunteers showed no evidence of side‐effects. Bovine FGF was i.m. administered in children with mental retardation caused by perinatal hypoxia, aged 1–15 years, at dosages of 0–4 or 0–28 μ.g kg−1, once or twice a month, over 7–12 months. Group A [n= 12; 6 treated (T), 6 controls (Ct)], group B (n= 16; 8 T, 8 Ct) and group C (n = 67; 45 T, 22 Ct) were evaluated with the P. A. R. scale, the WISC‐RM and the Gesell scale, respectively. Development increased significantly in treated children from groups A (P < 0.02) and C (P < 0.001), and IQrose by more than 10 points (P < 0.001) in group B patients.
Excursión diafragmática como predictor de éxito para el retiro de la ventilación mecánica en el paciente obeso Diaphragmatic excursion as a predictor of success in the removal of mechanical ventilation in obese patient Mobilidade diafragmática como preditor de sucesso na remoção da ventilação mecânica no paciente obeso
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