A 15‐year‐old, 9 g, female Mexican redknee tarantula (Brachypelma hamorii) presented to the North Carolina State University College of Veterinary Medicine with a history of anorexia and weight loss. Physical examination revealed an inability to extend the left chelicera, which was suspected to prevent the tarantula from prehending live prey. Magnetic resonance imaging revealed enlargement and T2 hyperintensity of the left chelicera. The patient was provided with supplemental feedings and rehydration until it was found deceased more than 8 months after the initial presentation. A postmortem examination was performed, and histopathology showed an area of chronic inflammation at the level of the left chelicera. Magnetic resonance imaging can be used as an antemortem diagnostic tool to identify lesions in tarantulas.
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