The first clinical photon-counting detector CT system demonstrated superior spatial resolution relative to current CT systems and improved noise properties and multi-energy temporal resolution relative to similarly configured, energy-integrating detector CT. Key Results1. The high-resolution mode of the photon-counting detector (PCD) CT demonstrated 125-micron in-plane spatial resolution and 0.3 mm longitudinal resolution, the smallest reported to date for a clinical CT system.2. The PCD CT system provided 66-msec temporal resolution multi-energy imaging in dual-source mode.3. Noise reduction (up to 47%) or dose reduction (up to 30%) were achieved in study participants using the PCD CT system relative to a similar CT system equipped with conventional detectors.

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We demonstrate the first (to our knowledge) general purpose full-field reflection-mode extreme ultraviolet (EUV) microscope based on coherent diffractive imaging. This microscope is capable of nanoscale amplitude and phase imaging of extended surfaces at an arbitrary angle of incidence in a noncontact, nondestructive manner. We use coherent light at 29.5 nm from high-harmonic upconversion to illuminate a surface, directly recording the scatter as the surface is scanned. Ptychographic reconstruction is then combined with tilted plane correction to obtain an image with amplitude and phase information. The image quality and detail from this diffraction-limited tabletop EUV microscope compares favorably with both scanning electron microscope and atomic force microscope images. The result is a general and completely extensible imaging technique that can provide a comprehensive and definitive characterization of how light at any wavelength scatters from a surface, with imminent feasibility of elemental imaging with few-nanometer resolution. OCIS codes: (120.5050) Phase measurement; (180.0180) Microscopy; (180.7460) X-ray microscopy; (190.2620) Harmonic generation and mixing. http://dx.