A series of fully or partially protected alkyl and aryl4,6-0( 1,1,3,3-tetraisopropyI-1,3-disiloxane-1,3-diyl)-~-glycopyrides and l-thio-/3-r@ucopymosides, respectively, were glycosylated by acetylated a-D-glucopymosyl-, galactopyranosyl-and cellobiosyl fluoride under Lewis acid-catalysis to give the corresponding #I-( 1+6)-linked di-and trisaccharides, respectively, in moderate to high yield. With benzylated glucopyranosyl fluoride, anomeric mixtures of disaccharides were obtained depending on the solvent that was used for the glycosylation step. The initially formed oligosaccharides having a l-fluore 1,1,3,3-tetraisopropyl-1,3disiloxane-3-y1 substituent at position 4 were converted by treatment with tembutylammonium fluoride into the corresponding 4-OH compounds whch are suitable as glycosyl acceptors for further extension of the sugar chain. Selective gl ycodesil ylation of methyl 2-~benzoyl-6-Odimethylthexylsilyl-3,4-O (1,1,3,3-tetraisopropyl-l,3-disiloxane-l~-diyl)-a-D-glu~pyranoside at position 6 without affecting positions 3 and 4 was possible under similar conditions. 4,6-O( 1,1,3,3-tetraisopmpyl-1,3disiloxane-l,3-dlyl)-protected Dglycopymnosyl donors (fluoride, chloride, trichloroacetimidate and ethyl 1-thieglycoside) of glucose and mannose were also p r e p a r e d and used for the construction of the corresponding silylated disaccharides. Regioselective ring opening of the silylated glycosides by pyridine-polyhydmgen fluoride gave useful gtycosyl acceptors that were subsequently coupled with 2,3,4,6-tetra-&eetyl-a-Dglucopymnosyl trichlomacetimidate.