On 21 August 2017 at 20:57 (local time) a very shallow (H = 1.2 km), moderate (Md = 4.0), earthquake hit the volcanic island of Ischia (Southern Italy), causing the death of two people. The study of the damage to the buildings with the European Macroseismic Scale 98 (EMS-98), carried out immediately after the earthquake, highlighted that hilly area of Casamicciola Terme, on the northern side of the Mt. Epomeo, was the most damaged part of the island with locally quite relevant damage (I = VIII EMS). This seismic event is the first damaging earthquake in Ischia during the instrumental era. In fact, this provides, for the first time, the opportunity to integrate historical seismicity, macroseismic observations, instrumental information, and detailed mapping of the geological coseismic effects. In this work we evaluate the effects induced by the 2017 Casamicciola earthquake on the environment using the Environmental Seismic Intensity 2007 (ESI-07) macroseismic scale. This macroseismic analysis, together with the superficial coseismic faulting characteristics and the available geophysical information, allows us to reconsider the source model for the 2017 earthquake and the previous damaging historical earthquakes in the Casamicciola Terme area. The application of the ESI scale to the Casamicciola Terme earthquake of 21 August 2017 and the assignment of seismic intensity offers better spatial resolution, as well as an increase of the time window for the assessment of the seismic hazard, allowing to reduce the implicit uncertainty in the intensity attenuation laws in this peculiar volcano-tectonic setting. Since intensity is linked to the direct measure of damage, and it is commonly used in hazard assessment, we argue that building damage at Casamicciola Terme is strongly influenced by earthquake surface faulting and near field effects, and therefore controlled by the geometry of the seismic source.
Background The hereditary cancer syndromes represent overall <10% of all cancers. These syndromes are not irrelevant for public health because all the cancers typical of these syndromes affected young people and many members of the same family and the cancers are more aggressive than the sporadic ones and need specific surgery and medical therapy. We developed a new family assessment tool: STELO designed for family physicians to identify patients could benefit from Cancer Genetic Counselling. Objective Test the sensitivity and specificity of a new assessment tool for the correct identification of inherited cancer syndromes. Methods Retrospectively we tested the new tool on a subset of patients who had already undergone genetic counselling at the Cancer Genetic Counselling Service of ASST (Azienda Socio Sanitaria Territoriale) Settelaghi Varese, to investigate sensitivity, specificity and applicability of this new tool in routine genetic screening. STELO responses were matched against the opinion of two cancer geneticists (i.e. gold standard) who blinded each other decided if the history of these patients was properly suspected as a hereditary cancer syndrome. Results The Genetic Counselling Service followed 546 subjects from 2014 to 2015. STELO tool was tested retrospectively on these clinical records and resulted positive in 418 cases, out of 546 (76.5%). STELO reported, towards the gold standard, 88.5% and 52.3% of sensitivity and specificity, respectively. Conclusions STELO has demonstrated to have a good sensitivity. The specificity was expectedly low given that STELO has been developed for general medicine, so it needs to be simple, practical, of rapid consultation and effectively used in clinical practice.
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