Background and aims:The results of epidemiological studies on dairy products and low-grade inflammation are scarce and inconsistent. Some studies have suggested that the associations may vary depending on the type of dairy product consumed. The aim of this cross-sectional study was to investigate the associations between intake of fermented and non-fermented dairy products and separately butter and serum high-sensitivity C-reactive protein (hs-CRP), a common inflammation marker, among a population with high dairy intake. Methods: The study included 1338 generally healthy men aged 42e60 years and serum hs-CRP 10 mg/L from the Kuopio Ischaemic Heart Disease Risk Factory Study, examined in 1984e1989. Dietary intakes were assessed using 4-day food records. ANCOVA and linear and logistic regression were used for analyses.Results: The reported mean intakes of fermented and non-fermented dairy products and butter were 189 (SD 217), 522 (SD 330) and 33 (SD 27) g/d, respectively. In the model adjusted for age, year of examination and energy intake (Model 1), higher intake of total dairy, total non-fermented dairy, total milk and butter were associated with higher concentration of serum hs-CRP, whereas fermented dairy intake was not associated with serum hs-CRP. After further adjustment for potential confounders, only higher butter intake remained statistically significantly associated with increased serum hs-CRP (P-trend ¼ 0.049). The odds ratio for elevated hs-CRP (>3 mg/L) in the highest vs. the lowest quartile was 2.50 (95% confidence interval 1.19e5.26, P-trend ¼ 0.02). Conclusions: These results suggest that high intake of butter, but not other dairy products may be associated with increased low-grade inflammation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.