CORRIGENDUM Milani GP et al. (2016) Using a high-flow nasal cannula provided superior results to low-flow oxygen delivery in moderate to severe bronchiolitis. Acta Paediatr 105: e368-72. doi: 10.1111/apa.13444. In the article 'Using a high-flow nasal cannula provided superior results to low-flow oxygen delivery in moderate to severe bronchiolitis', the formula reported to calculate the nasal cannula flow is incorrect. The formula used to calculate the flow rate (L/minute) of the high-flow nasal cannula was 8 mL/kg * respiratory rate / 0.3 / 1000. The authors apologise for this error.

Interleukin (IL)-5 is a potent mediator of the inflammatory cascade in the allergic response. Its predominant role in atopic reactions makes this cytokine an ideal target for blocking the eosinophilic inflammatory hyper-responsiveness to allergens. The management of allergic diseases in childhood-such as severe asthma, atopic dermatitis, and eosinophilic esophagitis-is a challenge. In particular, there are concerns regarding the use of high-dose corticosteroids. Over the last few years, biologics targeting IL-5 or IL-5 receptor-that are mepolizumab, reslizumab, and benralizumabrepresent a new, promising, and more personalized therapeutic option.

BackgroundPosterior reversible encephalopathy syndrome is a potentially reversible clinicoradiologic syndrome characterized by headache, mental confusion, visual disturbances and seizures associated with posterior cerebral lesions on radiological imaging. Prompt treatment of this condition is mandatory to avoid severe irreversible complications.Case presentationWe report a 9-year-old boy with arterial hypertension and headache as unique clinical presentation of posterior reversible encephalopathy syndrome.ConclusionsSevere and isolated headache associated with arterial hypertension can be the unique clinical presentation of posterior reversible encephalopathy syndrome. This syndrome must be considered even in absence of all typical symptoms to prevent the progression of a potentially life threatening condition.