Ag old(I)-catalyzed cascade [3,3]-propargylic rearrangement and [4+ +2] cycloaddition reaction of 2-vinylindoles with propargylic estersi sr eported. Ther eactionl eads to the synthesis of highly substituted tetrahydrocarbazole derivatives in high yields and diasteroselectivities. Furthermore,ap reliminary screeningf or an asymmetric version of this reaction is described.

Gold(I)-Catalyzed Synthesis of Tetrahydrocarbazoles via Cascade [3,3]-Propargylic Rearrangement/[4 + 2] Cycloaddition of Vinylindoles and PropargylicEsters. -Highly substituted tetrahydrocarbazole derivatives are obtained in high yields and diastereoselectivities. Furthermore, a preliminary screening for an asymmetric version of this reaction is also described. -(PIROVANO*, V.; ARPINI, E.; DELL'ACQUA, M.; VICENTE, R.; ABBIATI, G.; ROSSI, E.; Adv. Synth. Catal. 358 (2016) 3, 403-409, http://dx.doi.org/10.1002/adsc.201500913 ; Sez. Chim. Org. "A. Marchesini", Univ. Studi Milano, I-20133 Milano, Italy; Eng.) -T. Stabingis 24-135