On 11 March 2020, World Health Organization has made the assessment that COVID-19 can be characterized as a pandemic. COVID-19 is a usually self-limited infection but it can be present a severe and fatal disease in patients with comorbitidies and the elderly. The characteristics of the virus and general health condition of the host determine disease progression. Scientists have been investigating on the pathophysiology of this disease, diagnostic tools, effective treatment protocols, and the development a vaccine. Preventive strategies are as important as the treatment modalities. This review focuses on the pathophysiological mechanisms of COVID-19, in addition to the roles of exercise in the immunomodulatory mechanisms, host defense systems, and also prevention and treatment of COVID-19. Exercise exerts many important effects such as immunomodulation, augmented defense system on the immune system via mainly muscle derived myokines and increased cardiorespiratory endurance. CO-VID-19 pandemic once again demonstrated the importance of prophylactic approaches such as healthy life, maintaining and strengthening of health, and immune system modulation. This pandemic may start a period in which humanity prioritizes healthy living principles, functional foods, maintaining health and welfare approaches, and increased effort to develop and maintain them.
Gastrocolic fistula formation is an extremely rare complication of gastric adenocarcinoma. Here we reported a 65-year-old man who was admitted with recent onset halitosis and weight loss. Radiologic and endoscopic examinations revealed gastric cancer fistulizing transverse colon. The tumor was unresectable and the patient died in a short time after diagnosis.Résumé La formation d'une fistule gastrocolique est une complication extrêmement rare d'un adénocarcinome gastrique. Nous signalons ici le cas d'un homme de 65 ans qui a été admis avec une halitose d'apparition récente et une perte de poids. Les examens radiologiques et endoscopiques avaient révélé un cancer gastrique fistulé dans le côlon transverse. La tumeur était irrésécable et le patient est décédé dans un court laps de temps après le diagnostic.Mots clés Fistule gastrocolique · Cancer gastrique · Halitose · Perte de poids
Telemedicine—the utilization of clinical data and innovation to progress distanced clinical care can change the patient-centered approach. Telemedicine can coordinate distance monitoring and diagnostic instruments with computerized cooperation and suggestions to better interact with patients when they are not in a hospital. Despite these preferences, there is still some doubt as to how telemedicine applications may affect care. Guaranteeing that telemedicine is ethically admissible requires projection and consideration of four potential issues: the disruption of the patient-physician relationship, jeopardizing patient privacy, impelling one-size-fits-all applications, and the impulse to expect that innovation should be efficient
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