In this real-life study, 32% of patients received an inappropriate dose of DOAC. Several clinical factors can identify patients at risk of this situation.

Infective endocarditis on pacemaker devices has shown an increasing incidence during the past decades, representing almost 10% of all IE in the last 6 years. This is a severe disease, with a high rate of severe complications and requiring removal of device in most cases. In spite of therapy, early mortality is high.

A large percentage of apples are wasted each year due to damage such as bruising. The apple journey from orchard to supermarket is very complex and apples are subjected to a variety of static and dynamic loads that could result in this damage occurring.The main aim of this work was to carry out numerical modelling to develop a design tool that can be used to optimise the design of harvesting and sorting equipment and packaging media to reduce the likelihood of apple bruise formation resulting from impact loads. An experimental study, along with analytical calculations, varying apple drop heights and counterface material properties, were used to provide data to validate the numerical modelling.Good correlation was seen between the models and experiments and this approach combined with previous work on static modelling should provide a comprehensive design tool for reducing the likelihood of apple bruising occurring.

No abstract

In this study, HT recipients showed significantly lower values of average radial left ventricle strain, evaluated by means of 2DSTE, with the presence of ACR.