This literature review aimed to analyze the effectiveness of open inquiry learning on students' scientific attitude. Open inquiry learning is a learning model has the most complex level of scientific inquiry that gives students the opportunity to be able to identify errors, submit suggestions, to support or reject according to existing theories, computed chemical data through a mathematical process, and concepts so that students can improve their ability to investigate independently in open inquiry and students are able to carry out supervision and self-correction. The method of this study is a literature reviews were analyzed of the thirty two articles with the keywords which are used in the search are scientific attitude and open inquiry learning with a span of time from 2005 to 2020. This in-depth literature review uses the several steps: selection of the articles, analysis the article studies and categorization. Based on the literature review, students' scientific attitude will enhance through clear instructions which involve students to design the chemistry learning activities. This finding indicated that open inquiry learning activities effective to improve students' scientific attitude.
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