Introduction. Pomegranate is an old fruit which has many antimicrobial compounds. Impact of pomegranate peel extracts on Escherichia coli clinical isolate from Benha general hospital was investigated in this study. Material and Methods: pomegranate peel extraction was primed and GC/MS chromatogram analysis was carried out using the GC Agilent Technologies gas chromatography fitted with HP-5 fused silica column (25mm × 0.25mm, film thickness of 0.25 µm) and interfaced to the flame-ionization detector (FID). The antibacterial potential of Pomegranate peel extractions against E.coli sample was done using well diffusion method. Results: According to (GC/MS) technique, methanol and aqueous extracts of pomegranate peel have inhibitory effects on E. coli isolate. The minimum inhibition concentrations (MICs) of methanolic and aqueous extracts were 100 and 60 mg/L, respectively. In this study , the MICs values of Aqueous extract of pomegranate peel were higher than of methanolic extract of pomegranate peel (P<0.05). Zones of inhibition and values of MICs indicated that the aqueous extract of pomegranate peel had more effect on E. coli isolate than methanolic extract of pomegranate peel. Conclusion: In this study, the extraction of pomegranate peel has antibacterial effect on E.coli isolate. However, the aqueous extract had a higher effect on E.coli than the methanolic extract.
Plants have been used since ancient times in folk medicine, involving all medical traditions. Many plants and plant derived antimicrobial components are used in folklore therapeutics for oral hygiene. Salvia officinalis and Aloe vera extracts were assayed for the evaluation of their antimicrobial activity against two pathogenic bacteria that were identified biochemically and by VITEK2 system. The test of antibiotic susceptibility showed the resistance of the two isolates to at least ten antibiotics used in this study. In vitro investigations of nine Egyptian plant extracts showed that ethanolic Aloe vera and ethanolic Salvia officinalis extracts could exhibit an antibacterial activity against human pathogenic isolates and inhibition zones of 16.333±0.58 and 13.0 ±1.0 mm were observed when Salvia officinalis extract applied against the above-mentioned bacteria, while the inhibition zones of 13.333±0.58 and 11.667±0.58 mm were observed by Aloe vera extract.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.