The review of domestic and foreign literary sources for 2002–2014 made it possible to deepen into the problem of interstitial cystitis and put together different points of view and also to systematize the store of knowledge. Interstitial cystitis is a complex disease with marked clinical manifestation and defeat of urinary bladder with varying severity. For the purpose of diagnostics and treatment optimization of the disease in point in the review they presented the criteria whose existence will make it possible to make the diagnosis of interstitial cystitis. The multifactorial etiology of the disease requires the multiplane causal and pathogenetic therapy but more often empirical and symptomatic. In the article describe the algorithm of treatment of patients with the diagnosis of interstitial cystitis.
Контакты: Филипп Андреев ич Коссов fil-doc@yandex.ru
Введение. Стандартная биопсия предстательной железы (ПЖ) с последующей гистологической верификацией в настоящее вре-мя является неотъемлемой частью диагностики рака ПЖ (РПЖ),
Suspicious lesions were reported on both TRUS (hypoechoic lesion (HEL)) and MRI (!PI-RADS v2 score 3) in 69% of patients. More lesions per patient were found on MRI compared to TRUS (1.49 vs. 1.03, p<0.01). PI-RADS 3, 4, and 5 MRI lesions were seen as HEL on TRUS in 51%, 69%, and 85% of patients, respectively. PCa and clinically significant PCa were detected in 84% and 5% of PI-RADS 3 lesions, 80% and 49% of PI-RADS 4 lesions, and 93% and 79% of PI-RADS 5 lesions, respectively. SBx detected the highest overall Gleason score or was equivalent to MBx/TBx in 135 patients (67%). The highest overall Gleason score was detected in 17 patients (8%) by TBx, and in 13 patients (6%) by MBx. In 36 patients (18%) no PCa was found by any biopsy method.CONCLUSIONS: In the setting of high expertise and experience with TRUS and TBx, MRI and MBx do identify some additional high-grade cases, but this is not common, and the incremental value of MBx over SBx and TBx is relatively modest. SBx should not be omitted routinely from biopsy protocols, and urologists should not abandon TRUS as an important diagnostic imaging modality.
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