When resuscitated patients with STEMI are being evaluated in the emergency department, serious consideration should be given to emergent angiography and revascularization, regardless of neurologic status.
Utilization of a PTFE-covered stent may be a reasonable short- and long-term option to manage acute coronary perforation that occurs during PCI. On the basis of this limited experience, successful PTFE-covered stent deployment as the conclusive treatment for coronary perforation is associated with a favorable long-term event-free survival rate.
In this work, a compact transport model has been developed for monolayer transition metal dichalcogenide (TMDC) channel MOSFET. The analytical model solves the Poisson's equation for the inversion charge density to get the electrostatic potential in the channel. Current is then calculated by solving the drift-diffusion equation. The model makes gradual channel approximation to simplify the solution procedure. The appropriate density of states obtained from the first principle density functional theory simulation has been considered to keep the model physically accurate for monolayer TMDC channel FET. The outcome of the model has been benchmarked against both experimental and numerical quantum simulation results with the help of a few fitting parameters. Using the compact model, detailed output and transfer characteristics of monolayer WSe FET have been studied, and various performance parameters have been determined. The study confirms excellent ON and OFF state performances of monolayer WSe FET which could be viable for the next generation high-speed, low power applications. Also, the proposed model has been extended to study the operation of a biosensor. A monolayer MoS channel based dielectric modulated FET is investigated using the compact model for detection of a biomolecule in a dry environment.
Objectives
To assess the impact of aggressive protocol to decrease door-to-balloon (DTB) time on the incidence of false-positive STEMI (FP-STEMI) and in-hospital mortality.
Patients
Consecutive patients with presumed STEMI with confirmed ST-segment elevation that underwent emergent catheterization.
Methods
In July 1, 2009 we instituted an aggressive protocol to further reduce DTB time. A quality improvement (QI) initiative was initiated in January 1, 2010 to maintain short DTB while improving outcomes. Outcomes were compared before and after aggressive DTB and similarly before and after the QI initiative. Outcomes were DTB time, the incidence of FP-STEMI and in-hospital mortality. A review of the emergency catheterization database over the last 10 years (January 2001-December 2010) was carried out for historical comparison.
Results
Between July 1, 2008 and December 1, 2012, 1031 consecutive patients with presumed STEMI were assessed. Of these 170 were considered FP-STEMI. The median DTB time decreased from 76 to 61 minutes with the aggressive DTB protocol (P=. 001), accompanied by an increase of FP-STEMI (7.7% vs. 16.5%, p=.02). While TP-STEMI in-hospital mortality witnessed non-significant reduction, this was associated with a significant increase of FP-STEMI in-hospital mortality. After the QI initiative, a shorter DTB time (59 minutes) was maintained while decreasing FP-STEMI in-hospital mortality.
Conclusion
Aggressive measures to reduce DTB time were associated with an increased incidence of FP-STEMI and FP-STEMI in-hospital mortality. Efforts to reduce DTB time should be monitored systematically to avoid unnecessary procedures that may delays other appropriate therapies in critically ill patients.
We investigate the performance of a micro gap vacuum thermionic energy converter considering the loss mechanisms due to the space charge effect and interelectrode radiative heat transfer. The dependencies of the space charge effect and near-field radiative heat exchange on the interelectrode distance are derived based on established theories. The electrode temperatures are determined by solving the steady-state energy balance equations in a numerical, iterative process and considering a constant energy flux input to the emitter. The resultant behaviour of the different mechanisms of energy flow from the electrodes is studied for a wide range of interelectrode distances, which provides new insights into the device operation.The maximum efficiency of the converter is obtained by optimizing the operating voltage and interelectrode distance. Considering the interplay between space charge and near-field radiative heat transfer, an optimal range is determined for the interelectrode distance. The optimal value of the distance and the lower limit of this range are found to be significantly higher than previously reported, where constant electrode temperatures had been assumed.
Semiconductors have been used in solar energy conversion for decades based on the photovoltaic effect. An important challenge of photovoltaics is the undesired heat generated within the device. An alternative approach is thermionics, which uses the thermal excitation of electrons from an emitter to a collector across a vacuum gap. If the emitter is a p-type semiconductor, the photogeneration-induced quasi-Fermi level splitting can reduce the effective barrier for electron emission—a mechanism used by a photon enhanced thermionic emission device. Here, we evaluate the prospects of this alternative solar conversion technology considering different semiconductor materials and thermionic device configurations. We also reveal that whether such a device operates in the photon enhanced or purely thermionic mode, depends on the complex interplay among materials properties, device physics and solar concentration level.
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