Methods: Retrospect ive analysis of 47 patients of oral tongue squamous cell carcinoma treated surgically and pathologica lly staged as T2N0 with clear margins. The study period was from March 2004 to March 2011. Treatment outcome was evaluate d in terms of was locoregio nal recurre nce, disease free survival and overall survival. Kaplan Meir survival curves were used for the analysis. The mean follow up period was 28.3 months.Results: Recurrences occurred in 13 out of 47 patients (27.7%). At 5 years the overall survival is 80.5% and disease free survival is 53.9%. Univariate analysis revealed two significant prognost ic predictors for disease free survival: perineural invasion (PNI, p = 0.037) and lymphov ascular invasion (LVI, p = 0.05). This two factors did not have an effect on overall survival (p = 0.717).
Conclusion:In oral tongue cancer (pT2N0), PNI and LVI significantly increased the recurre nce rate without an impact on surviva l. Prospect ive studies with large patient numbers are needed to evaluate this further and to see if adjuvant therapeuti c strategies need to be changed .
Necrotizing fasciitis is a quickly progressing soft tissue infection that can be described with diffuse necrosis of subcutaneous tissue and superfi cial fascia. The cause of this can be infectious process of odontogenic origin, most commonly caused by mixed gram+ and gram-, aerobic and anaerobic microorganisms that are found in patients that are predisposed to infections. In a case of undiagnosed illness, there is a possibility of life threatening complications. This case analysis introduces the diagnostic criteria of the disease and treatment plan, encouraging doctors to devote more attention to prevention of infections.A.E 72-year-old man, was treated in the department of head and neck surgery of RECUH (Riga East Clinical University Hospital) LOC (Latvian Oncological Center) with Clinical Case: Necrotizing Fasciitis of the neck after surgery of a Mandibular Radicular Cyst
Communicated by Andrejs SkaìersData from 35 patients were analysed to identify the main factors that may have predisposed the unfavourable clinical course in early diagnosed lower lip cancer. Of 35 patients who were sent to the Oncology Centre of Latvia, Rîga East University Hospital, with the diagnosis of early lower lip cancer, histologically diagnosis was confirmed for 22 patients. Sizes of the primary tumours were less than 2 cm (T1 size tumour). Vermilionectomy was carried out for 17 patients, wedge-or Vshaped resection was performed for 13 patients, and in five cases patients refused to receive surgical treatment and received radiation therapy instead. Review of the reports of the histological criteria for patients with aggressive course of the illness with relapses, regional metastases and also in cases of death, showed that vermilionectomy can be considered an effective diagnostic and therapeutic operation.
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