Purpose
The purpose of this study is to explore the association between intake of different types of dietary fats with breast cancer (BC) risk in Iranian women.
Design/methodology/approach
A total of 540 women (180 women with BC and 360 healthy women) were recruited from Shohadaye Tajrish hospital, Tehran, Iran. Data on anthropometric measurements, physical activity, smoking and alcohol consumption were collected. The food frequency questionnaire was used to assess the intake of fatty acids including saturated fatty acids, mono unsaturated fatty acids, poly unsaturated fatty acids, macronutrients, total fat, cholesterol, and calorie.
Findings
The cases had significantly higher BMI (29.19 ± 3.2 vs 27.27 kg/m2 ± 2.8) and higher intake of calorie (2737 ± 925 vs 2315 ± 1066 kcal/d, P = 0.01), carbohydrate (402 ± 125 vs 312 ± 170 kcal/d, P = 0.01) and ω−6 fatty acids (5.45 ± 6.9 vs 3.39 ± 0.59 g/d, P = 0.001) compared to the control group . Higher consumption of ω−6 fatty acids was related with higher risk of BC (OR = 5.429, CI95%:2.5–11.79, P = 0.001) The association between BC and intake of omega-6 fatty acids remained significant after adjustments for age, BMI, for using alcohol drinks, smoking, physical activity, calorie intake, protein intake and carbohydrate intake.
Originality/value
There are insufficient studies to investigate the association of different types of fatty acids with BC. This study found that higher omega-6 fatty acids intake was associated with increased risk of BC in women.
Background: Dyslipidaemia is a group of abnormalities that predispose people to heart disease. The index of nutritional quality (INQ) is a tool for qualitative and quantitative nutritional assessment, which has special significance in assessing clinical nutritional problems. The objective of this study was to determine the association between the INQ and lipid profile in adult women.Methods: This was a cross-sectional study on 360 healthy women referring to the nutrition clinic of Shohadaye Tajrish hospital, Tehran, Iran. Calorie and nutrient intake were assessed using a validated food frequency questionnaire. The amount of physical activity was estimated using a validated International Physical Activity Questionnaire. To measure serum lipid levels, 5 ml of venous blood samples was taken from the participants.
Results:The results showed a negative association between total cholesterol and the INQ of niacin (B = −0.110, p = .02) and between high-density lipoprotein cholesterol with the INQ of biotin (B = −0.119, p = .01). Also, a positive association was found between triglyceride and the INQ of B6 (B = 0.096, p = .04). The results remained
Introduction. Gastric bypass surgery is a gold standard therapy for severe obesity. This study aimed to evaluate anthropometric predictors for short-term excess weight loss (EWL) after Roux-en-Y gastric bypass surgery (RYGB) in a sample of severely obese patients. Materials and Methods. This cohort study was conducted on severely obese candidates for RYGB bariatric surgery in Mashhad, Iran. Indirect calorimetry, anthropometric measurements, and body composition data were collected before, one, and six months after RYGB. Results. Fifty-four participants (43, 79.6% women and 11, 20.4% men) with a mean age of 39.63 ± 9.66 years participated in this study. The mean total weight and BMI loss within six months were 32.89 ± 20.22 kg and 12.37 ± 7.34 kg/m2, respectively. The mean reduction in adipose tissue and fat-free mass was 24.49 kg and 7.46 kg, respectively. The mean resting metabolism rate (RMR) reduction at one and six months after RYGB was 260.49 kcal and 396.07 kcal, respectively. There was a significant difference in mean RMR between the baseline and one and six months after RYGB (
p
<
0.001
). There was no significant gender difference in mean weight and BMI loss percentage at six months post-RYGB (
p
>
0.05
). Baseline skeletal muscle mass (SMM), excess BMI loss (EBMIL) at first month after surgery, and baseline neck circumference (NC) could predict EWL six months after surgery. Conclusion. Reduced RMR shortly after RYGB may be due to FFM reduction. Some anthropometric and their acute changes after RYGB may predict the short-term EWL in RYGB patients.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.