Childhood vaccination is a highly effective public health intervention for reducing childhood mortality and morbidity. This review discusses the factors that have been shown to influence vaccination uptake in Africa. African countries should develop effective strategies to address failures and challenges faced with vaccination uptake and hesitancy for it to achieve high vaccination coverage and reduction of vaccine preventable diseases.This is particularly important because of the likely short-term decline in foreign aid due to the economic recession arising from the prevailing coronavirus disease 2019 pandemic.
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