Background: Klatskin tumor is a rare liver cancer that involves the bile ducts. Its incidence begins to increase over time and is usually only diagnosed in patients who are already at an advanced stage. The annual incidence of klatskin tumors is not more than 1:100,000. Klatskin tumor is suspected based on signs of biliary obstruction, ultrasonography showing a stricture or bile mass, cholangiography with ERCP and MRCP, abnormal liver function tests, and elevated tumor marker CA 19-9. Case Report: A 65-year-old man presented to the hospital with complaints of yellowing of the eyes and body that began one month ago, as well as a lump in the right upper abdomen that had grown larger over the previous five months. Physical examination revealed yellow eyes, and a palpable lump in the upper quadrant of the patient's abdomen. The patient defecates looked like putty and urinates looked like tea. The diagnosis leaded to a klatskin tumor because the results of MRCP showed a mass in the hilar region of the liver that extended to the proximal common bile duct, which described the appearance of a klatskin tumor. There were an increasing CA 19-9 level and liver function tests. Conclusion: Patient has been diagnosed with klatskin tumors, has choledocholithiasis risk factor, supported by appropriate MRCP images and increasing CA 19-9 level
Background: Inflammation and dyslipidemia play an important role in the formation of atherosclerotic plaques in stable coronary artery disease (SCAD). The stenosis degree indicates a visual evaluation of the percentage reduction of coronary diameter compare to normal coronary. This study aims to determine the correlation of lipid profiles, CRP with the stenosis degree in SCAD. Methods: Cross sectional study was carried in 31 patients with SCAD who had coronary angiography at Dr. Kariadi. The study used secondary data from February-March 2018 at Dr. Kariadi Semarang. Secondary data included levels of total cholesterol, LDL, HDL, triglycerides and CRP. The stenosis degree was obtained from coronary angiography in percentage units. Statistical analysis used Latar Belakang: Inflamasi dan dislipidemia berperan penting dalam pembentukan plak aterosklerotik pada penyakit jantung koroner (PJK) stabil. Derajat stenosis menunjukkan evaluasi visual dari persentase pengurangan diameter relatif terhadap segmen normal yang berdekatan. Penelitian ini bertujuan untuk menganalisis hubungan profil lipid dan C-Reactive Protein (CRP) dengan derajat stenosis koroner pada penyakit jantung koroner stabil. Metode: Penelitian potong lintang pada 31 penderita PJK stabil yang telah dilakukan angiografi koroner di RSUP Dr. Kariadi. Penelitian menggunakan data sekunder dari bulan Februari-Maret 2018 di RSUP Dr. Kariadi Semarang. Data sekunder meliputi kadar kolesterol total, LDL, HDL, trigliserida dan CRP. Derajat stenosis koroner diukur berdasarkan angiografi koroner dalam Spearman Correlation test, p < 0,05 was considered significant. Result: Median (min-max) levels of total cholesterol, HDL, LDL, triglycerides, CRP and stenosis degrees respectively are 156 (104-283), 41 (13-67), 102 (60-190), 116 (60-216), 1.50 (0.50-6.54), 70 (20-100). Correlation of total cholesterol, HDL, LDL, triglycerides and CRP levels with a degree of coronary stenosis are (r = 0.123; p = 0.511), (r =-0.132; p = 0.479), (r = 0.073; p = 0.697), (r = 0.117; p = 0.531), (r = 0.026; p = 0.891). Conclusion: There are no significant correlation between lipid profiles, CRP with stenosis degree in SCAD. The effect of statin drugs has an effect on dyslipidemia and as an anti-inflammatory. satuan persentase. Uji statistik menggunakan korelasi Spearman, p < 0,05 dianggap bermakna. Hasil: Median (min-maks) kadar kolesterol total, HDL, LDL, trigliserida, CRP dan derajat stenosis secara berturut-turut yaitu 156 (104-283), 41 (13-67),
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