Many fruits of the Myrtaceae have a rich history of use both as edibles and as traditional medicines in divergent ethnobotanical practices throughout the tropical and subtropical world. From South America to Southeast Asia, these fruits have been used for a wide variety of ailments, including cough, diabetes, dysentery, inflammation and ringworm. These same fruits are also used to make many food products. Based on information regarding ethnomedical use, known phytochemistry, fruit color, popularity as edibles and availability, the fruits of several edible species from the subtribe Eugeniinae have been selected for phytochemical analysis in an attempt to discover new antioxidants. The fruits of six species in this group have shown a strong antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl chemical assay. The UV absorbance spectrum of the most active compound in Eugenia uniflora L. indicates that it is a flavonoid. Polyphenolic compounds like flavonoids have an enormous range of biological activity and are known to inhibit oxidative damage in vivo better than the classical vitamin antioxidants. In plants, they protect against lipid peroxidation and UV damage that can affect tropical fruits growing under severe conditions including high heat and intense sunlight.
Dendrobium is a genus of flowering plants belonging to the Orchidaceae family with more than 1,400 species. Many Dendrobium species have been used as medicinal plants in several Asian countries for thousands of years. Alkaloids were reported as the major biological markers due to their complex chemical compositions and various types. In this review, we summarized the structural types of alkaloids, their pharmacological activities, as well as the mechanisms of biological activities. More than sixty alkaloids were isolated and identified from the Dendrobium genus. Moreover, the pharmacological effects of Dendrobium alkaloids as hepatic lipid and gluconeogenesis regulation, as neuroprotection, and as anti-tumor, anti-inflammatory, anti-diabetes, and anti-virus factors were described. Besides, the total chemical synthesis of dendrobine is provided, while the biosynthetic pathway of dendrobine has been proposed based on the functions of associated genes. For applications of these invaluable herbs, more researches on the extraction of biological markers from compounds are needed. Further confirmation of the proposed biosynthetic pathways is anticipated as well.
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