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BackgroundPenetrating trauma of the neck and face is a frequent presentation to acute emergency, trauma and critical care units. There remains a steady incidence of both gunshot penetrating injury to the neck and face as well as non-missile penetrating injury—largely, but not solely, knife-related. Optimal imaging assessment of such injuries therefore remains an on-going requirement of the general and specialised radiologist.MethodsThe anatomy of the neck and face—in particular, vascular, pharyngo-oesophageal, laryngo-tracheal and neural anatomy—demands a more specialised and selective management plan which incorporates specific imaging techniques.ResultsThe current treatment protocol of injuries of the neck and face has seen a radical shift away from expectant surgical exploration in the management of such injuries, largely as a result of advances in the diagnostic capabilities of multi-detector computed tomography angiography (MDCTA), which is now the first-line imaging modality of choice in such cases.ConclusionThis review aims to highlight ballistic considerations, differing imaging modalities, including MDCTA, that might be utilised to assist in the accurate assessment of these injuries as well as the specific radiological features and patterns of specific organ-system injuries that should be considered and communicated to surgical and critical care teams.Teaching points• MDCTA is the first-line imaging modality in penetrating trauma of the neck and, often, of the face• The inherent deformability of a bullet is a significant factor in its tissue-damaging capabilities• MDCTA can provide accurate assessment of visceral injury of the neck as well as vascular injury• Penetrating facial trauma warrants radiological assessment of key adjacent anatomical structures• In-driven fragments of native bone potentiate tissue damage in projectile penetrating facial trauma

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Summary Five previously unreported families in which cases of primary hyperoxaluria have occurred have been investigated to determine whether an hereditary pattern is apparent in this disease. The occurrence of the condition in sibs in the absence of any detectable abnormality in the parents has been proved in two of these families, and suggests a recessive mode of inheritance. In one family out of a total of eight which have now been reported from our laboratories the parents of the propositus are first cousins. The sex‐incidence of the disease appears to be approximately equal.