No abstract

Age-specific risk of recurrent stroke for various risk factors, calculated independently, was estimated using the first year of data from the Lehigh Valley Stroke Register. The register is based on a population of more than one-half million. Among the risk factors examined, the highest overall risk of recurrent stroke, 41.4, occurred with a history of at least one transient ischemic attack (TIA). After myocardial infarction (MI), the relative risk of a recurrent stroke was 8.0, while with all other heart diseases combined it was 8.4. With diabetes, the relative risk of a recurrent stroke was 5.6; with hypertension, it was 4.5. The relative risk increased with age after TIA and MI, but not for other heart disease, diabetes, and hypertension, except in the 85+-year-old age group.

Highlights d Eusocial African naked mole-rats raise colony-nest CO 2 to anticonvulsant levels d Naked mole-rats harbor an epilepsy-related variant in neuronal Clextruder KCC2 d GABA-acting antiseizure drug diazepam triggers seizures in naked mole-rats d Diazepam is rendered seizure-suppressing in nest-like levels of CO 2 in inhaled air

No abstract