Este estudo caso-controle teve como objetivo identificar os fatores que modificam o risco de câncer de próstata em pacientes de um hospital público da Paraíba. Dados de 91 pacientes e 91 controles saudáveis pareados por idade (± 5 anos) foram obtidos de prontuários médicos e entrevistas pessoais. A razão de chance e os intervalos de confiança foram determinados por meio de análise de regressão. Pacientes e controles tinham em média 69,56 (DP = 8,31) e 68,32 (DP = 7,68) anos (p = 0,297). Afrodescendentes e homens que já fumaram, tiveram um risco 4,150 e 3,939 vezes maior (p
<p>Cashew apple presents a characteristic astringency. However, the compounds responsible for this characteristic were not described yet. A cashew apple extract was added to a BSA solution and the compounds before and after precipitation were analyzed by UPLC-QTOF/MS<sup>E</sup>. The extract astringency was measured on a 5-point scale (0: non astringent and 4: extremely astringent). Among the phenolics detected anacardic acids were identified and evaluated for their astringent effect. In the sensorial tests the cashew apple extract was considered very astringent (average of 2.5). A mixture of anacardic acids, had an average of 1.76 (astringent). The three isolated anacardic acids were evaluated. The <i>in silico</i>experiments were performed to analyze mainly the steric factor associated to the binding. The sensory results were confirmed by <i>in silico</i> analysis, indicating that a higher unsaturation degree of the aliphatic chain leads to an astringency increase.</p>
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