Marengo Fuentes for granting me his trust, time, dedication and direction at all times, and especially for the endless patience he gave me during the long period of time that I needed to complete this thesis. I would like to express my deepest gratitude to my family. Their supportive role was priceless. Thanks to Lourdes De Gracia and Liliane Yi. They were fundamental to maintain my mind on the right place during this time. Also, my thanks to David Murcko who is always there to support me when there is too much stress. Last but not least, to my friends an colleaguesÀngels Borràs, BengisuÖzbay, Sadjad Asghari-Esfeden and Romil Shah, who are the closest people to a brother that I have here in the United States of America.
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