To validate the use of multiplex case families in studying the pathogenesis of systemic lupus erythematosus (SLE), we investigated the pattern of familial SLE in relation to sporadic SLE in the highly consanguineous Kuwaiti population. We sought to determine whether familial and sporadic SLEs have the same clinical and serological features. We compared 21 cases of familial SLE in 21 families with 42 non-familial SLE controls matched for age, sex and duration of disease. Twenty-one families, in which the diagnosis of SLE was verified in at least two relatives, were included in the study. The diagnosis was made according to the revised 1982 American College of Rheumatology criteria. There were no significant differences in clinical features or serological manifestations between familial SLE cases and their matched controls. However, our results showed that the frequency of La/SSB antibodies was higher in the sporadic group (P = 0.048), although this was not significant after application of Bonferroni's correction for the number of comparisons. Familial cases of SLE were more likely to present at younger age of 20 years and sporadic cases at 26 years (P = 0.006). The prevalence of familial SLE was 27.4%. We have found that familial and sporadic cases of SLE are broadly similar, and it is justified to include multiple case families in genetic studies.

The study was conducted to find out the effect of dried garlic (Allium sativum) powder at different levels on the productive and reproductive performance of local quail. About ninety female local quail were used. The quails were divided into six groups (control, standard diet + 3% lipid, standard diet + 2% powder garlic, standard diet + 2% powder garlic + 3% lipid, standard diet + 4% powder garlic, and standard diet + 4% powder garlic + 3% lipid). A higher significance (p≤0.05) in egg weight (11.69 g/egg), feed intake (2977.13 g/week), hen day egg production (92.48 %), and egg mass (10.62) was recorded of quail eating (4% powder garlic). The results show the significant (p≤0.05) superiority of quails fed 4% of garlic powder in the internal egg characteristics such as egg albumen weight, yolk height, Haugh unit, and egg hardness. A significant (p≤0.05) improvement in the blood lipid profile in favor of quail birds fed on rations containing dried garlic powder, as the highest value for total cholesterol, triglycerides, LDL, and VLDL found in the treatment of birds fed on high lipids, while the highest values ​​of HDL were in the treatments of fed different levels of garlic powder. The highest levels of Ghrelin, T4, and LH, hormones were recorded for quail birds fed with 2% garlic powder. Birds fed on high lipid diet showed higher concentrations of leptin and growth hormone, while the higher value of FSH was seen in a 4% garlic supplemented diet. We conclude from the above that birds fed 4% dried garlic powder were superior in most productive and reproductive traits, compared to other treated birds.

This study was conducted on 90 local quail females in six different treatments in order to know the effect of adding green tea powder to the quail diet on the productive, reproductive, biochemical and hormonal characteristics of quail females. The results showed a significant superiority of the birds of the group fed on 1% of green tea powder in hot and cold carcass weight, average egg weight, albumin weight, yolk height and color, and the lowest feed consumption, while the control-treated birds in the number of eggs produced, HDP, ALT, Alkaline and Bilirubin exceeded the other treatments birds. Concerning the lipid profile, blood urea ratio, and AST, the highest significant figures were recorded in the treatment of birds fed a ration to which 3% lipids were added. In contrast, the lowest values ​​for total cholesterol, Tri, VLDL, and blood nitrogen were recorded for birds of the treatment fed at 2% of green tea powder. The results showed that there were significant differences between the six treatment birds in the level of blood hormones, as the highest level of (estrogen), (Ghrelin, leptin, FSH), (T4) and (Growth and LH) were recorded for the control birds, 3% lipid and 1% dried green tea and 2% green tea with 3% lipid, respectively. We conclude from the above that birds fed a supplemented diet of 1% green tea powder were superior in most productive and reproductive traits, especially carcass weight, dressed %, egg weight and internal egg characteristics, compared to other treated birds.

The present study was done to assess the effect of the tetralogy of Fallot (TOF) on some arterial blood measurements including pH, the partial pressure of carbon dioxide (PaCO2), the partial pressure of oxygen (PaO2), Base excess (BE), Red blood cells (RBC), Packed cell volume (PCV), and Hemoglobin (Hb) concentration in the Erbil City of Iraq. For this purpose 80 (40 males and 40 females) patients with (TOF) and aged between 3-33 years were used in this study. This retrospective cohort study was conducted from March /2018 to October 2020 and carried out in the Surgeries Hospital Specialist -Cardiac Center in Erbil city. The studied parameters were estimated before and two to three weeks after postoperative correction of TOF. A dependent ttest was used for data analysis. The results showed that males and females with (TOF) after surgical correction have significantly p≤ 0.001 lower PaCO2, RBC, PCV, and Hb concentration, while the concentration of PaO2 and the value of BE were significantly p≤ 0.001 higher after surgical correction in comparison with the value before surgery. Moreover, males showed a significantly higher concentration of RBC, PCV, and hemoglobin than females after surgical correction. Conclusions: Surgery repair of (TOF) restore the arterial blood measurements PaCO2, PaO2, BE, RBC, PCV, and Hb concentration to the normal value in males and females.