This study investigated the two-body wear resistance of a first generation 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP), a second generation 3Y-TZP, a third generation 4 mol% yttria partially stabilized zirconia (4Y-PSZ), a 5 mol% yttria partially stabilized zirconia (5Y-PSZ), and a type III gold alloy (Aurocast 8), performed using opposing antagonistic cusps made out of the same material. Eight cylindrical specimens were prepared for each material (n = 8) for a total of forty specimens (N = 40). Conical cusps were fabricated for each material. Each cylinder–cusp pair was arranged inside a two-axis chewing simulator over up to 360,000 loading cycles. The wear resistance was analyzed by measuring the vertical substance loss (mm) and the volume loss (mm3). The antagonist wear (mm) was recorded before and after the wear test to evaluate the linear difference. Statistical analysis was performed using one-way analysis of variance (ANOVA); multiple comparisons were performed according to Tukey’s method. No statistically significant differences (p > 0.05) among the first generation 3Y-TZP, second generation 3Y-TZP, and 4Y-PSZ wear were found. 5Y-PSZ showed statistically significant higher wear compared to other the zirconias. Aurocast 8 displayed the highest values in terms of vertical wear, antagonist cusp wear, and volumetric loss. Although still not statistically comparable, the wear behavior of the latest 5Y-PSZ was the closest to the widely recognized gold standard represented by the type III gold alloy.

Lithium disilicate (LDS) glass ceramics are among the most common biomaterials in conservative dentistry and prosthodontics, and their wear behavior is of paramount clinical interest. An innovative in vitro model is presented, which employs CAD/CAM technology to simulate the periodontal ligament and alveolar bone. The model aims to evaluate the effect of the abutment rigidity on the wear resistance of the LDS glass ceramic. Two experimental groups (LDS restorations supported by dental implants, named LDS-on-Implant, or by hybrid ceramic tooth replicas with artificial periodontal ligament, named LDS-on-Tooth-Replica) and a control group (LDS-Cylinders) were compared. Fifteen samples (n = 15) were fabricated for each group and subjected to testing, with LDS antagonistic cusps opposing them over 120,000 cycles using a dual axis chewing simulator. Wear resistance was analyzed by measuring the vertical wear depth (mm) and the volume loss (mm3) on each LDS sample, as well as the linear antagonist wear (mm) on LDS cusps. Mean values were calculated for LDS-Cylinders (0.186 mm, 0.322 mm3, 0.220 mm, respectively), LDS-on-Implant (0.128 mm, 0.166 mm3, 0.199 mm, respectively), and LDS-on-Tooth-Replica (0.098 mm, 0.107 mm3, 0.172 mm, respectively) and compared using one-way-ANOVA and Tukey’s tests. The level of significance was set at 0.05 in all tests. Wear facets were inspected under a scanning electron microscope. Data analysis revealed that abutment rigidity was able to significantly affect the wear pattern of LDS, which seems to be more intense on rigid implant-abutment supports compared to resilient teeth replicas with artificial periodontal ligament.