Nowadays some efforts are being made to reduce obesity by using drugs that aim to reduce appetite of the drug users. However, the use of drugs still has harmful side effects. Endophytic fungi originating from the Dayak onion plant are thought to have secondary metabolites that have potential as anti-obesity. The aims of this study were to determine the compounds produced by endophytic fungi of Dayak onion and to determine the potential components as inhibitors of pancreatic lipase enzymes. Samples of Dayak onions were collected from Palangka Raya using purposive sampling method. Isolation of endophytic fungi was conducted using surface sterilization method and the isolates were grown on PDA. Isolates were characterized and fermented on PDB for 14 days. The selected isolate was analyzed by using GCMS then molecular docking was performed using Autodock Vina and PyRx. The research results showed that there were 7 isolates of endophytic fungi isolated from leaves and roots tissues of Dayak onion. GCMS analysis showed that EBD1 contains 38 compounds. Molecular docking analysis showed that 1,3-Di-O-Acetylpentopyranose, a test ligand, has the closest binding affinity value (-6.6 kcal/mol) to orlistat (control) (-6.8 kcal/mol). Thus, it has the potential as an inhibitor of pancreatic lipase enzyme protein.
Perairan rawa gambut Kalimantan merupakan salah satu habitat bagi keragaman ikan air tawar, dimana keragaman ikan air tawar ini saat ini mengalami berbagai ancaman kepunahan yang disebabkan oleh penyakit dan patogen, polusi perairan, perubahan suhu dan iklim, laju deforestasi, dan degradasi habitat. Inventarisasi dan pengenalan jenis merupakan langkah awal dalam melestarikan keragaman jenis ikan air tawar. Tujuan dari penelitian ini adalah untuk menginventarisasi jenis ikan air tawar yang terdapat di kawasan Universitas Palangka Raya. Penelitian dilakukan selama 1 Februari -30 April 2021 pada tiga titik pengamatan di Kawasan Sungai Universitas Palangka Raya dengan menggunakan metode penangkapan secara langsung pada lokasi pengamatan. Hasil pengamatan menunjukkan 2574 individu yang terdiri dari 8 famili, 11 genus, dan 15 spesies. Kelimpahan jenis ikan air tawar ditunjukkan pada jenis Pectenocypris korthausae dengan 1114 individu. Kata kunci : ikan air tawar; inventarisasi; Kalimantan; rawa gambut; Universitas Palangka Raya.
Freshwater prawn species Macrobrachium lanchesteri (De Man, 1911) in Kalimantan for the first time was reported to be found only in East Kalimantan and there have been no reports of this species being found in Central Kalimantan. This study aims to reveal the presence of invasive freshwater prawn and habitat characteristics found in the watershed of Palangka Raya University. This study was conducted in October–November 2019 covering five stations. Specimens were collected using a purposive sampling method. Environmental parameter measurements were made including types of substrate, water velocity, tree cover, water depth as well as width. The identification of specimens from the watershed of Palangka Raya University based on morphological characteristics shown that the species very similar to the alien freshwater prawn, M. lanchesteri. Based on the results of research, this report has revealed the presence of this invasive species in Central Kalimantan, Indonesia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.