Aortic valve replacement with a pulmonary autograft (ie, Ross procedure) is a technique used in selected cases for the treatment of aortic valve disease. Aware of reports describing chronic complications after the Ross procedure such as aortic insufficiency, right ventricular outlet obstruction, aortic autograft dilatation, and pulmonary allograft stenosis, cardiac magnetic resonance imaging (MRI) was performed in individuals who had a previous Ross procedure (range 2 to 10 years earlier) to determine if these complications could be visualized by MRI. This case study presents the MRI findings of 5 patients (mean age: 42.0+/-7.8 years). In each patient, complications of the Ross procedure were observed. These results suggest that cardiac MRI has the potential to become a clinically important technique for evaluating post-Ross procedure patients.
In vivo coronary artery imaging remains technically difficult in mice and only a few studies have been reported so far. 3D method is usually time-consuming and presents a practical limitation for MRI study of coronary arteries in mouse models of various cardiovascular diseases. The current study aims to develop a rapid and robust 2D procedure to visualize both LCA and RCA of mice in vivo. In addition, contrast agent of Gd-DPTA by rapid intraperitoneal (i.p.) injection was examined for its ability to improve the quality of LCA and RCA visualization. The current study demonstrated the feasibility of rapid MRI examination of coronary arteries of mice in vivo using 2D method and i.p. injection of contrast agent.
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