The Internet of Things (IOT) system is a network system that communicates with other devices and systems via the web by using any one of the sensors, devices, applications, and other tools. To prevent unauthorized data transmission access, these systems and networks should include a suitable cryptography mechanism. The security of the shared resources on the data communication network is regarded as one of the key challenges. In this paper, the proposed scheme consists of two parts: (i) generating a key using an array of prime numbers based on the RSA algorithm, and (ii) devising a secure communication scheme based on DNA cryptography and Insertion Method. DNA cryptography is a cryptographic technique that uses DNA sequences to encode and decode source data using biological processes. It is an innovative way to protect data from hackers using DNA. The proposed scheme's security analysis shows that it is secure against the relevant threat models and provides a higher level of protection than previous related studies in the literature.
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