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Although the composition of blood is assumed to be constant within narrow limits, fluctuations in concentration of its constituents have been found by many observers over the period of a day or longer. Shaw (1927), Jores (1934) and others describe daily fluctuations in the white corpuscles, and Sabin et al. (1925) found similar changes in the blood platelets.The literature dealing with diurnal fluctuations in the red blood corpuscles (R.B.C.) is already large and has been recently reviewed by Branwood (1946). Changes over longer periods of time have been described by Platt & Freeman (1930) In the present study an attempt is made to determine whether a true diurnal rhythm (significant diurnal variation) is present for blood haemoglobin concentration (Hb), haematocrit value, plasma protein concentration, erythrocyte sedimentation rate (E.S.R.), and blood chloride concentration. Data are also presented to show variation over longer periods of time. Much of the material was not considered suitable for statistical analysis, and the data offered is mainly that dealing with repeated assays on the same individual (intra-individual variability), and with groups studied on the same day (group variability). A small amount of data obtained from sick individuals and from a few animals is given for comparison.

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The post-war need for large numbers of dwellings has promoted renewed inquiry into the basic criteria by which good practice in the design and construction of buildings may be judged. More emphasis than ever before is now being put upon the functional characteristics of buildings regarded as living-spaces rather than as structures.