Soft tissue sarcoma are here, heterogeneous malignant neoplasms that present difficulties in diagnosis, treatment and follow-up. High-quality diagnostic planning allows timely decision-making on further tactics of patient management in a particular case. Positron emission tomography with a biological analogue of glucose – 18F-fluorodeoxyglucose, combined with computed tomography, is an imaging tool that measures the metabolic activity of a tumor and is increasingly used in clinical practice to assess primary tumor tissue, staging, monitoring the effectiveness of treatment and as a method of early detection of relapses. This literature review is aimed at evaluating the usefulness of positron emission tomography combined with computed tomography at different stages of diagnostic control in patients with soft tissue sarcomas.
Synovial sarcoma (SS) is a rare malignant soft tissue tumor that is associated with a high risk of distant metastasis, which significantly reduces patients` life expectancy. The analysis of volume indicators of PET/ CT)with 18F-fluorodeoxyglucose (FDG) was performed in two patients with the same grade of SS malignancy. The presented clinical cases demonstrate that in different patients with similar values 18F- FDG of the standardized uptake value (SUVmax) PET/CT volume indicators such as Metabolic Tumor Volume (MTV) and Total Lesion Glycolysis (TLG) can vary significantly, and therefore they can be additional prognostic factors for overall survival.
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