The Black Sea-South Caspian megadepression is a vast region includes large geological structures developed during the Meso-Cenozoic time and have both a single development history and a different one. Based on the chemistry of volcanic rocks and seismic data, to determine the genesis of the geological structures that make up the Black Sea-South Caspian megadepression, its evolution and the presence of minerals an attempt was made. Large modern geostructural elements, such as the Riony, Kura, West Turkmenian, Black Sea and South Caspian depressions, which are part of the megadepression, have united into a single whole as a result of processes taking place on the margin Tethys Ocean. Based on the analysis of volcanic rocks buried under Cenozoic sediments, the picture of the ancient ocean margin development and its subsequent history were modeled. Favorable conditions for the generation and accumulation of hydrocarbons, formed as a result of all processes, led to the fact the entire Black Sea-South Caspian megadepression has a huge reserve of these minerals.
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