Abstracts e465 ing both new medical and psychological symptoms as they age. However, there has been very little information written about this phenomenon, although late onset medical problems have been documented, particularly in the Australian Rubella population born in the 1940 s. The results of this study are helpful in understanding both medical and psychological symptoms of the CRS adults, and anticipate potential diseases and behaviors.
Background:The incidence of device-related osteoarticular infections (DROI) is expected to rise, according to the increasing number of devices implanted. The appearance of DROI increases economic costs of arthroplasty and greatly affects the patientś life quality. The aim of this study is to describe the etiology and patterns of antibiotic sensitivity of the microbiological isolates, the surgical and medical treatment, and the clinical evolution of first episode of DROI episodes.Methods & Materials: Retrospective descriptive study of patients with DROI between July 2015 and December 2016. The microbiological diagnosis was performed by mass spectrometry, automated antibiogram and agar diffusion confirmation. Quantitative variables are reported as median and interquartile range(ICR), and categorical variables are reported as n and percent. For statistical analysis EpiInfo7.2 ® was used.Results: During the analyzed period, 32 patients were treated for DROI in our center, 18(56%) were women. The median age was 67 years(ICR 44-74). Thirteen(41%) patients had at least 1 risk factor. Twelve(37.4%) had early infections. Twenty-five(78%) had prosthetic joint infections and 7(22%) had device-related spine infections. The most frequently affected joints were: hip: 17(68%), knee: 6(24%), others: 2(8%). Surgical interventions were: toilette with material retention: 14(45%), toilette with material partial removal: 2(6%) and toilette with material removal: 15(49%). Most frequent microbiological isolates (n = 31): Staphylococcus aureus(S.aureus): 14(45%), coagulase-negative staphylococcus(CoNS): 9(29%), Enterobacteriaceae: 4(13%). Fifty percent of S.aureus were methicillin-resistant. Eight of 9 CoNS were found in late infections. Antibiotic resistance is reported in table 1. Mean intravenous treatment days was 14. Median oral treatment months was 4(ICR 3-6).
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