Studied relationship in serum concentration of testosterone and lipids in 35 men with a positive coronarographic finding and 30 sterile men, in comparison with a control group. From lipid parameters we determined serum concentration of cholesterol, triacylglycerols and apolipoprotein B, and lipid distribution in lipoprotein fractions.Serum testosterone concentration was found decreased in both the group as against the controls. As to lipid parameters, cholesterol concentration was depressed in the high-density lipoprotein (HDL) fraction of both the clinical groups. As increased apolipoprotein B level was seen in men with the positive coronarographic finding.The results point to a negative effect of lowered testosterone concentrations on lipid metabolism.
The author presents an unusual case of general sepsis of the organism caused by periurethral abscess in a 38 years old man. The aetiology is discussed.
The frequency of individual congenital anomalies of the deferens, the seminal vesicles, the ejaculatory ducts and the utricle in 158 patients treated for sterility was determined by the method of deferentovesiculography by punction. Congenital anomalies were found in 14 patients (8.8%). Anomalies of rare occurrence are demonstrated in detail. The relation of such anomalies to sterility of patients is described.
Relationships between plasma testosterone levels and selected parameters of lipid metabolism were studied in a group of young sterile males prior to, during, and after hormone therapy. Initial hypertriacylglycerolaemia and decreased concentrations of HDL cholesterol returned to normal values after 30 days of methyltestosterone administration. LDL cholesterol concentrations decreased significantly as did plasma apolipoprotein B levels. These changes persisted also one month after cessation of treatment. The results suggest that restoration of initially decreased testosterone levels in the studied group of sterile males is associated with the restoration of the lipid profile.
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