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THE following notes on poisoning by .primula obconica were suggested by a case which lately came under my care. The patient, who came to see me on 23rd September, 1898, was a lady who was very fond of gardening, and had in her greenhouse some fine young plants of primula obconica which she tended daily. For the seven previous weeks she had had irritable red patches on the wrists ~nd forea::ns, with here and there the surface broken.The eruption came out suddenly, appearing on the wrists and lower half of the forearms within twenty-four hours. In a few days it died away from the arms, and, as it did, Ca:he out at the back and sides of the ankles ; in about a month the rash recurred on the wrists and arms, and had, when I saw her, remained out for about three weeks, although the plants were no longer being tended. The rash varied in appearance--sometimes it was urticarious, sometimes eczematous, and occasionally papules formed and passed on into pustules. There were attacks of intolerable itching, and sometimes of severe neuralgic pain; and all the time, whether the rash was visible or not, the patient had epigastric tmeasiness and felt sick and out of sorts.The progress was slow; bathing the affected regions with very hot water, and the application of dilute citrine ointment giving most relief.

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