Acute fatty liver of pregnancy is a rare condition that occurs during the third trimester of pregnancy. Formerly regularly fatal, this pathology currently benefits from a better maternal and fetal prognosis, , due to earlier diagnosis, rapid delivery and symptomatic treatment. An observation is reported of a case which presented at a late stage after having developed a frank cutanocellular jaundice with significant hypertransaminasemia and thrombocytopenia and a drop in PT with a rapid progression to a picture of hepatocellular insufficiency associating a hepatic encephalopathy and hemostasis disorders.
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