Intensity Modulated Radiation Therapy (IMRT) provides the ability to not only conform the radiation dose to the shape of the target thereby reducing dose to normal tissues, it also allows to deliver different doses each day to different parts of the target. This approach is known as a simultaneous integrated boost (SIB). This study aims that dosimetric parameters of SIB with IMRT treatment planning technique are compared with conventional treatment planning technique using NTCP for 2 head and neck cancer patients.
The aim of the study is to evaluate radiation doses of left-sided whole-breast irradiation on left-sided anterior descending coronary artery (LAD) among various radiotherapy treatment planning techniques for 45 left-sided breast cancer patients. METHODS Three different radiotherapy techniques, field-in-field, 4-field inverse IMRT, and 5-field IMRT, were undertaken. For inverse IMRT, the fields were special for each patient. We used 2 opposed tangential beams in the field-in-field technique, and for the other two techniques, the beams were obtained by 10° refraction. RESULTS The 5-field IMRT technique is not useful for decreasing the LADmax dose. We figured out that in the field-in-field technique, 18 of our 45 patients received doses greater than 10 Gy to LAD. We also found that using the 4-field inverse IMRT technique, LAD and lung doses could be reduced. CONCLUSION The mean LADmax dose was smaller than 10 Gy for all techniques except the field-in-field technique. There was no significant difference between 4-field inverse IMRT and field-in-field techniques. However, if LAD is located deeper than 2.5 cm, the LADmax dose could increase; this could further be decreased to under 10 Gy using the 4-field inverse IMRT technique.
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