Abstract-The amount of liquid intake in neonatal care should be preceded by the knowledge of the neonate hydro-balance. A reduced liquid intake can cause dehydration, electrolytic unbalance and hypotension. By the other hand, an excessive intake can cause peripheral edema, congestive heart failure, among others problems. Thus, the assessment of the liquid compartment in neonates, by a non-invasive, non-expensive and fast method can contribute to increase the quality of the neonatal care. Bioimpedance has been used to assess fluid volumes in adults, but a very few works has been published in neonatal studies, specially using techniques able to observe the intra and extra-cellular compartments separately. The present work aims to study the fluid balance in neonates using a recent bioimpedance spectroscopy method and correlate the results with clinical findings.
Abstract-Current approaches for auditory screening are usually based on the Brainstem Auditory Evoked Potentials or on the Otoacoustic Emissions, and hence are not able to detect pathologies that affect higher auditory centers. Therefore, the Middle Latency Auditory Evoked Potential (MLAEP) was investigated as a neurophysiologic acoustic threshold measure by using the "Evoked Potential Detector" (EPD) as an Objective Response Detection technique. The EEG was collected from ten adults during monaural click stimulation (left ear, using contralateral masking noise) with different sound pressure levels. Based on the statistical distribution of EPD under the null hypothesis (absence of response), the use of the critical value considering EEG as a colored noise and fitting the shape parameters for a Beta distribution resulted in an objective detection of MLAEP with a better specificity and a similar sensitivity than considering EEG as a white noise. Full detection over all the casuistry occurred for stimulation levels as low as those found in literature using expert-based analysis, particularly for the derivation contralateral to the stimulation. This finding suggests the use of EPD for detecting MLAEP response as an auxiliary tool for determining objectively the neurophysiologic acoustical threshold level.
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