The biological (antiviral) activity of a dried purified extract of Stevia was evaluated in vitro. Tests were performed using Teschen disease virus, infectious rhinotracheitis virus, and human coronavirus.
A new approach to the formulation of eye drops containing the active substance taurine and adjuvant polymers such as dextran, poly(hexamethyleneguanidine) hydrochloride, and Sovidon is proposed. According to this, the eye drop formulation must begin with a study of the physicochemical properties of the polymer and taurine solutions, in particular an evaluation of their surface tension and wettability of a substrate similar to the mucous layer of lacrimal film. The optimal values of the solution concentrations providing effective drug delivery into the intracellular space of epithelial cells were determined.
Dzhusа volcanogenic massive sulfide deposit is characterized by a high concentration of dykes of basic and intermediate rocks. Thermal metamorphism of ore and recrystallization of ore minerals were caused by formation of post-ore dykes. It was shown that homogenization temperature regular increased from 156 °С at a distance of the dyke to 287-305 °С in its contact zone. Highly saline (6,4-15,7 wt.% eq. NaCl) water fluids saturated with CO2 suggest high pres- sure conditions (up to 1500 bars) and can result from contact and regional metamorphism.
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