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Vol. 61 activity showed a tendency to increase when the solutions were permitted to stand for some time. Certain solutions of the freshly prepared tyrosinase also showed this tendency to increase in activity on standing. 9. The ratio of activities of the tyrosinase preparations toward p-cresol and catechol could not be altered by various methods of purification, but always remained 10 to 1, respectively.The ratio of the two activities in the case of the solutions of the crystalline material was also 10 to 1. 10. Composition, similarity in absorption spectra, the slight increase in activity when solutions are allowed to stand, all point to a close relationship between the crystals and the highly purified tyrosinase preparations.New York, N. Y.

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