Surgery in TLE patients does not worsen the global psychopathological status. Presurgical psychiatric morbidity was found to be related to the presence of psychiatric disorders after surgery. Specific psychiatric assessment should be made before and after surgery.

Our findings show a different pattern of regional cerebral glucose metabolism between AVH and physiological auditory activation. This feature does not support the hypothesis that AVH in acute schizophrenic patients reflects an abnormal activation of auditory-linguistic pathways. However, it does suggest that cortical regions implicated in the generation of inner speech could be involved.

Cognitive function in adulthood is a complex interaction of neuronal pathways and neuroanatomic structures essential in human development. Although diverse factors have been described to interfere in cognitive function, several lines evidence support the fact that early life stressful events (abnormal intrauterine growth, infections, and placenta abnormalities) predict future cognitive impairments in adulthood.Currently, it is also considered that the perinatal stage can substantially modify the possibility of presenting different pathologies in adulthood. In parallel, the diagnosis of schizophrenia has been associated with a higher prevalence of perinatal stressors: obstetric complications, prenatal infections, labor difficulties, and postpartum complications [1]. Nowadays, the influence of perinatal complications of the patient with schizophrenia has expanded not only to diagnosis per se [2], but also to symptomatology, neuroimaging, metabolism [3] and cognitive function of the patient in adulthood.

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