This report showed an increase in transmitted DRMs in areas where antiretroviral drugs were introduced earlier, although other factors such as natural viral polymorphisms and acquired DRMs through exposure to antiretroviral cannot be totally excluded. Further surveillances are needed to confirm this evolution and inform public health policies on adequate actions to help limit the selection and transmission of drug-resistant HIV, while scaling up access to ART in developing countries.
Zembe et al.: The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono-and multi-clade epidemics: implications for HIV vaccine design. Retrovirology 2012 9(Suppl 2):P253.
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